Structure of PDB 6agi Chain A

Receptor sequence
>6agiA (length=303) Species: 9606 (Homo sapiens) [Search protein sequence]
ATSRERRFRLFASIECEGQLFMTPYDFILAVTTDEPKVTWKSLSKQELNQ
MLAETPPVWKGSSKLFRNLKEKGVISYTEYLFLLCILTKPHAGFRIAFNM
FDTDGNEMVDKKEFLVLQEIFRDEEKRAMLRLQLYGVTDTTLLVHFFGKK
GKAELNFEDFYRFMDNLQTEVLEIEFLSYSNGMNTISEEDFAHILLRYTN
VENTSVFLENVRYSIPEEKGITFDEFRSFFQFLNNLEDFAIALNMYNFAS
RSIGQDEFKRAVYVATGLKFSPHLVNTVFKIFDVDKDDQLSYKEFIGIMK
DRL
3D structure
PDB6agi Dimerization of MICU Proteins Controls Ca2+Influx through the Mitochondrial Ca2+Uniporter.
ChainA
Resolution2.799 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CA A D245 D247 N249 M251 E256 D102 D104 N106 M108 E113
BS02 CA A D483 D485 D487 Q489 E494 D283 D285 D287 Q289 E294
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0006851 mitochondrial calcium ion transmembrane transport

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Molecular Function

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Biological Process
External links
PDB RCSB:6agi, PDBe:6agi, PDBj:6agi
PDBsum6agi
PubMed30699349
UniProtQ86XE3|MICU3_HUMAN Calcium uptake protein 3, mitochondrial (Gene Name=MICU3)

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