Structure of PDB 6ag4 Chain A

Receptor sequence
>6ag4A (length=157) Species: 273057 (Saccharolobus solfataricus P2) [Search protein sequence]
DFTLRNARMDDIDQIIKINRLTLPENYPYYFFVEHLKEYGLAFFVAIVDN
SVVGYIMPRIEWGFSNIKQLPSLVRKGAVVSIAVLEEYRRKGIATTLLEA
SMKSMKNDYNAEEIYLAVRVSNYPAIALYEKLNFKKVKVLKGYYADGEDA
YLMARPL
3D structure
PDB6ag4 Adaptation of thermophilic acetyltransferase to a water-mediated catalytic mechanism.
ChainA
Resolution2.256 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.255: N-terminal amino-acid N(alpha)-acetyltransferase NatA.
2.3.1.258: N-terminal methionine N(alpha)-acetyltransferase NatE.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ACO A L33 I92 A93 V94 R99 R100 G102 A104 T105 P134 L138 Y139 K141 L23 I82 A83 V84 R89 R90 G92 A94 T95 P124 L128 Y129 K131
BS02 CA A R129 N132 R119 N122
Gene Ontology
Molecular Function
GO:0004596 peptide alpha-N-acetyltransferase activity
GO:0016746 acyltransferase activity
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups
GO:0046872 metal ion binding
GO:0120518 peptide-methionine-alpha-N-acetyltransferase activity
Biological Process
GO:0006474 N-terminal protein amino acid acetylation
Cellular Component
GO:0005737 cytoplasm
GO:0031415 NatA complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6ag4, PDBe:6ag4, PDBj:6ag4
PDBsum6ag4
PubMed32780067
UniProtQ980R9|NAT_SACS2 N-alpha-acetyltransferase (Gene Name=ard1)

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