Structure of PDB 6af6 Chain A

Receptor sequence
>6af6A (length=383) Species: 104623 (Prodigiosinella confusarubida) [Search protein sequence]
MDFNLSNSQSDIYESAYRFACDVLDQDAQTRISQKILSTELWKKAAAYGF
AHGPVSHQFGGSELGALDTALMIEALGKGSRDIGLSFSLCAHLCACVIPL
YRFGSSELKDKYLESLVTGKLIAANAATEPDAGSDIYNMQATAQPCEGGY
ILNGKKIFITNAPIADVFIIYAKTNPDHGFLGVSAFLIEKGTPGLNVGEV
IPKDCLSNCPWSEIVFNDIFIPQSQRIGMEGAGGAIFHDSMIWAKGCLSA
LFVGGLARLLETTLEYAKARQQFGKAIGQFQSVSNRIIDMKLRLEQCRLM
LYRACWKHDQGQDAEADIAMSKLLISEYAVQSGLDAIQTFGGAAMDQELG
LVRHLLNMIPSRIFSGTNDIQKEIIARKLGLRG
3D structure
PDB6af6 Crystal Structure of PigA: A Prolyl Thioester-Oxidizing Enzyme in Prodigiosin Biosynthesis.
ChainA
Resolution1.62 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) A127 T128 A244 R377
Catalytic site (residue number reindexed from 1) A127 T128 A244 R377
Enzyme Commision number 1.3.8.14: L-prolyl-[peptidyl-carrier protein] dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD A N125 A127 T128 G133 S134 F158 I159 T160 W211 I363 F364 T367 D369 I370 N125 A127 T128 G133 S134 F158 I159 T160 W211 I363 F364 T367 D369 I370
BS02 O4B A L41 K44 L41 K44
BS03 O4B A K275 F280 K275 F280
BS04 PRO A M241 S365 M241 S365
BS05 PRO A G133 I136 F237 G133 I136 F237
Gene Ontology
Molecular Function
GO:0003995 acyl-CoA dehydrogenase activity
GO:0016491 oxidoreductase activity
GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors
GO:0050660 flavin adenine dinucleotide binding
Biological Process
GO:0017000 antibiotic biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6af6, PDBe:6af6, PDBj:6af6
PDBsum6af6
PubMed30095206
UniProtQ5W271|PIGA_SERS3 L-prolyl-[peptidyl-carrier protein] dehydrogenase (Gene Name=pigA)

[Back to BioLiP]