Structure of PDB 6acx Chain A

Receptor sequence
>6acxA (length=1175) Species: 246196 (Mycolicibacterium smegmatis MC2 155) [Search protein sequence]
SVQTPIAGLVELALSDPSLQDVIRRAADRPADLALVGPASARVLVAAALA
QNGPLLVVAATGREADELTAELRGVFGDSVALFPSWETLPHERLSPGVET
VGARLMLLRRLARPDDETLGAPLRVVVTTTRSLLQPMAPDLVDIEPVTLS
VGAEMEFEDVVARLVDLSYTRVDMVGKRGEFAVRGGILDVFPPTAEHPVR
VEFWGDEISEMRAFAIADQRSIPEVPVQTVVAVPCRELLMTDDVRERAAA
LAAEHPTTENTVPGTVPDMLAKLAEGIPVDGMEALLPLLHPIEPTTLTRH
LPEGAPVLVCDPEKVRTRAADLIKTGREFLEASWSTAAVGGDAPIDLEAL
GASGFVTFEEAREAAREGGHPWWTLSQLSDESAVELDIRSAPSARGSQHN
LEEIFAMLRAHVATGGYAAVVTPGIGTAHRVVEQLGEADTAATILEPGTA
PKAGVVGVLKGPLCSGVVLPGANLVIITETDLTGNRVTAAAKRRNVVDPL
ALTAGDLVVHDQHGIGKFVEMTERVVGGARREYLVLEYASGTDKLYVPMD
SLDQLSRYVGGEAPSLSRLGGSDWANTKTKARRAVREIASELVALYAKRQ
SAPGHAFGPDTPWQAEMEDAFGFTETIDQLTAIQEVKSDMEKPVPMDRVI
CGDVGYGKTEIAVRAAFKAVQDGKQVAVLVPTTLLADQHLQTFTNRMAGF
PVTVKGLSRFTDPAESRAVIEGLKDGSVDVVIGTHRLLQTGVTWKDLGLI
IVDEEQRFGVEHKEHIKSMRTHVDVLTMSATPIPRTLEMSLAGIREMSTI
LTPPEERYPVLTYVGPHDDKQVAAALRRELLRDGQAFYIHNRVRTIDEAA
ARVRQLVPEARVVVAHGQMNEETLEKTVEGFWNREYDILVCTTIVETGLD
ISNANTLIVERADTFGLSQLHQLRGRVGRSRERGYAYFLYPPNKPLTETA
YDRLATIAQNNELGAGMAVAMKDLEIRGAGNVLGAEQSGHVAGVGFDLYV
RLVGEAVEAYRAAADGDVRIDLPVDAHLPPEYIGSDRLRLEAYRRLAAAA
DDDAVASVVDELIDRYGPLPEPAQRLVAVARLRLLCREFGITEIGAVSAS
TVRLSPMVLPDSAQLRLKRMYPGGHYRATTSTVQVPLPRAGEAPRIRDLE
LVQWVAGLVLVLNGKGQGDVDMSKF
3D structure
PDB6acx Structural basis for nucleotide-mediated remodelling mechanism of Mycobacterium Mfd
ChainA
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A F641 V672 G673 Y674 G675 K676 T677 P822 F623 V654 G655 Y656 G657 K658 T659 P804
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0003684 damaged DNA binding
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity
Biological Process
GO:0000716 transcription-coupled nucleotide-excision repair, DNA damage recognition
GO:0006281 DNA repair
GO:0006355 regulation of DNA-templated transcription
GO:0032508 DNA duplex unwinding
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6acx, PDBe:6acx, PDBj:6acx
PDBsum6acx
PubMed
UniProtA0R3C5

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