Structure of PDB 6aci Chain A

Receptor sequence
>6aciA (length=304) Species: 574521 (Escherichia coli O127:H6 str. E2348/69) [Search protein sequence]
RPSFAGKEYSLEPIDERTPILFQWFEARPERYEKGEVPILNTKEHPYLSN
IINAAKIENERIIGVLVDGNFTYEQKKEFLNLENEHQNIAIIYRADVDFS
MYDKKLSDIYLENIHKQESYPASERDNYLLGLLREELKNIPEGKDSLIES
YAEKREHTWFDFFRNLAILKAGSLFTETGKTGCHNISPCSGCIYLDADMI
ITDKLGVLYAPDGIAVHVDCNDEIKSLENGAIVVNRSNHPALLAGLDIMK
SKVDAHPYYDGLGKGIKRHFNYSSLHNYNAFCDFIEFKHENIIPNTSMYT
SSSW
3D structure
PDB6aci Structural and Functional Insights into Host Death Domains Inactivation by the Bacterial Arginine GlcNAcyltransferase Effector.
ChainA
Resolution1.87 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 UDP A Q48 W49 F50 Y72 F185 D221 D223 S322 S327 S328 W329 Q23 W24 F25 Y47 F160 D196 D198 S297 S302 S303 W304
BS02 MN A D223 N320 S322 D198 N295 S297
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0016757 glycosyltransferase activity
GO:0030145 manganese ion binding
GO:0046872 metal ion binding
GO:0090729 toxin activity
GO:0106362 protein-arginine N-acetylglucosaminyltransferase activity
Biological Process
GO:0034054 symbiont-mediated suppression of host defense-related programmed cell death
GO:0085034 symbiont-mediated suppression of host NF-kappaB cascade
Cellular Component
GO:0005576 extracellular region
GO:0030430 host cell cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6aci, PDBe:6aci, PDBj:6aci
PDBsum6aci
PubMed30979585
UniProtB7UI21|NLEB1_ECO27 Protein-arginine N-acetylglucosaminyltransferase NleB1 (Gene Name=nleB1)

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