Structure of PDB 6a9u Chain A

Receptor sequence
>6a9uA (length=405) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
GELTPGISALEYYERRIRLAETLPPKSCVILAGNDIQYPFQQENDLFYLS
GWNEPNSVMILEKPTDSLSDTIFHMLVPPFRSGVYGVQEIFNADESASIN
DLSKYLPKIINRNEFIYFDMLSSSNFKHIKSLLDNKTIKPISKRIAEFRK
IKSPQELRIMRRAGQISGRSFNQAFAKRFRNERTLDSFLHYKFISGGCDK
DAYIPVVATGSNSLCIHYTRNDDVMFDDEMVLVDAAGSLGGYCADISRTW
PNSGKFTDAQRDLYEAVLNVQRDCIKLCKASNNYSLHDIHEKSITLMKQE
LKNLGIDKVSGWNVEKLYPHYIGHNLGLDVHDVPKVSRYEPLKVGQVITI
EPGLYIPNEESFPSYFRNVGIRIEDDIAIGEDTYTNLTVEAVKEIDDLEN
VMQNG
3D structure
PDB6a9u Crystal structures and biochemical analyses of intermediate cleavage peptidase: role of dynamics in enzymatic function.
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.11.26: intermediate cleaving peptidase 55.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y296 D327 D338 H417 E444 E467 Y203 D234 D245 H324 E351 E374
BS02 MN A D327 D338 H413 E467 D234 D245 H320 E374
BS03 MN A D338 H417 E444 E467 D245 H324 E351 E374
Gene Ontology
Molecular Function
GO:0030145 manganese ion binding
GO:0070006 metalloaminopeptidase activity

View graph for
Molecular Function
External links
PDB RCSB:6a9u, PDBe:6a9u, PDBj:6a9u
PDBsum6a9u
PubMed30582634
UniProtP40051|ICP55_YEAST Intermediate cleaving peptidase 55 (Gene Name=ICP55)

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