Structure of PDB 6a89 Chain A

Receptor sequence
>6a89A (length=167) Species: 9838 (Camelus dromedarius) [Search protein sequence]
ACGSIVPRREWRALASECRERLTRPVRYVVVSHTAGSHCDTPASCAQQAQ
NVQSYHVRNLGWCDVGYNFLIGEDGLVYEGRGWNIKGAHAGPTWNPISIG
ISFMGNYMNRVPPPRALRAAQNLLACGVALGALRSNYEVKGHRDVQPTLS
PGDRLYEIIQTWSHYRA
3D structure
PDB6a89 Crystal structure of the ternary complex of peptidoglycan recognition protein (PGRP-S) with Tartaric acid, Ribose and 2,6-DIAMINOPIMELIC ACID at 2.11 A resolution
ChainA
Resolution2.11 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 RIB A S139 N140 S135 N136
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity
GO:0016019 peptidoglycan immune receptor activity
GO:0042834 peptidoglycan binding
Biological Process
GO:0001818 negative regulation of cytokine production
GO:0009253 peptidoglycan catabolic process
GO:0016045 detection of bacterium
GO:0042742 defense response to bacterium
GO:0045087 innate immune response
GO:0050830 defense response to Gram-positive bacterium
Cellular Component
GO:0005576 extracellular region

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External links
PDB RCSB:6a89, PDBe:6a89, PDBj:6a89
PDBsum6a89
PubMed
UniProtQ9GK12|PGRP1_CAMDR Peptidoglycan recognition protein 1 (Gene Name=PGLYRP1)

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