Structure of PDB 6a7i Chain A

Receptor sequence
>6a7iA (length=409) Species: 1525753 (Streptomyces sp. JS01) [Search protein sequence]
RLMTRIALDPFVRDLDGESAALRAAGPLAEVELPGGVHVYAVTRHAEARA
LLTDSRVVKDIDVWNAWRRGEIPMDWPLIGLANPGRSMLTVDGADHRRLR
TLVAQALTVKRVERLRAGIEALTNASLEKLAALPAGEPVDLKAEFAYPLP
MNVISELMGVDAADHPRLKELFEKFFSTQTPPEEVPQMMADLGALFTKIV
DAKRTNPGDDLTSALIAASENGDHLTDEEIVNTLQLIIAAGHETTISLIV
NVVEALQTHPEQRKKVLNGEIGWDGVIEETLRWNTPTSHVLIRFATEDIE
VGDKILPKGEGLIISFGALGRDEEQYGPTAGEFDATRTPNRHIAFGHGPH
VCPGAALSRLEAGIALPALYERFPELDLAVPASDLRNKPIVTQNDLHELP
VKLGCPFGG
3D structure
PDB6a7i Characterization of two steroid hydroxylases from different Streptomyces spp. and their ligand-bound and -unbound crystal structures.
ChainA
Resolution2.19 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) S175 E241 T242 C350 P351 G352
Catalytic site (residue number reindexed from 1) S177 E243 T244 C352 P353 G354
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEM A K57 M86 R98 I235 A238 T242 V288 R291 A342 F343 H348 C350 P351 G352 K59 M88 R100 I237 A240 T244 V290 R293 A344 F345 H350 C352 P353 G354
Gene Ontology
Molecular Function
GO:0004497 monooxygenase activity
GO:0005506 iron ion binding
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037 heme binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:6a7i, PDBe:6a7i, PDBj:6a7i
PDBsum6a7i
PubMed30552795
UniProtA0A087KD84

[Back to BioLiP]