Structure of PDB 6a2c Chain A

Receptor sequence
>6a2cA (length=518) Species: 35974 (Santalum album) [Search protein sequence]
NYPPNLWDYEFLQSLGDEKHLKLADKLKEEVKSLIKQTMEPLTKLEFIDT
VRRLGLKYQFETEVKEAVVMVSKYENDAWWIDNLHATSLRFRIMRENGIF
VPQDVFERFKDTDGFKNQLCEDVKGLLSLYEASFLGWEGEDILDEARTFA
TSKLKSIEGKIPSPSLAKKVSHALDLPLHWRTIRYEARWFIDTYEEEEDV
NLTLLRYAKLDFNIVQSFHQKEIGRLSRWWVGTGLDKMPFARNGLIQSYM
YAIGMLFEPNLGEVREMEAKVGALITTIDDVYDVYGTMEELELFTDITNR
WDISKADQLPRNIRMPLLTMFNTSNDIGYWALKERGFNGIPCTAKVWSDQ
LKSYTKEAKWFHEGHKPTLEEYLDNALVSIGFPNLLVTSYLLTVENPTKE
KLDYVNSLPLFVRASCILCRIINDLGTSPDEDNLKSIQCYMNEAGASQEV
AREHIEGLVRMWWKRLNKCLFEPSPFAEPFLSFTVNVVRGSHFFYQYAES
WTKKQGMSVLIHPIPLNE
3D structure
PDB6a2c Crystal structure of a synthase 2 from santalum album in complex with lig2
ChainA
Resolution1.94 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) R279 Y288 G309 D316 D320 S416 I417 G418 R457 N460 T464 E468 Y536
Catalytic site (residue number reindexed from 1) R242 Y251 G272 D279 D283 S379 I380 G381 R420 N423 T427 E431 Y495
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FPP A S285 Y288 G309 D316 I417 L422 R457 N460 S248 Y251 G272 D279 I380 L385 R420 N423
BS02 MG A D316 D320 D279 D283
BS03 MG A D316 D320 D279 D283
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0010333 terpene synthase activity
GO:0016829 lyase activity
GO:0046872 metal ion binding
Biological Process
GO:0016102 diterpenoid biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6a2c, PDBe:6a2c, PDBj:6a2c
PDBsum6a2c
PubMed
UniProtA0A0A0RCB5

[Back to BioLiP]