Structure of PDB 6a0f Chain A

Receptor sequence
>6a0fA (length=302) Species: 9606 (Homo sapiens) [Search protein sequence]
PLLVEGRRVRLPQSAGDLVRAHPPLEERARLLRGQSVQQVGPQGLLYVQQ
RELAVTSPKDGSISILGSDDATTSHIVVLRHTGNGATCLTHCDGTDTKAE
VPLIMNSIKSFSDQCGRLEVHLVGGFSDDRQLSQKLTHQLLSEFDRQEDD
IHLVTLCVTELNDREENENHFPVIYGIAVNIKTAEIYRASFQDRGPEEQL
RAARTLAGGPMISIYDAETEQLRIGPYSWTPFPHVDFWLHQDDKQILENL
STSPLAEPPHFVEHIRSTLMFLKKHPSPAHTLFSGNKALLYKKNEDGLWE
KI
3D structure
PDB6a0f Structural Analyses on the Deamidation of N-Terminal Asn in the Human N-Degron Pathway.
ChainA
Resolution2.384 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.1.121: protein N-terminal asparagine amidohydrolase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Q51 T73 T74 S75 L253 S254 T255 E260 I268 Q50 T72 T73 S74 L250 S251 T252 E257 I265
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0008418 protein-N-terminal asparagine amidohydrolase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0007613 memory
GO:0008344 adult locomotory behavior
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6a0f, PDBe:6a0f, PDBj:6a0f
PDBsum6a0f
PubMed31968674
UniProtQ96AB6|NTAN1_HUMAN Protein N-terminal asparagine amidohydrolase (Gene Name=NTAN1)

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