Structure of PDB 5zyw Chain A

Receptor sequence
>5zywA (length=233) Species: 9606 (Homo sapiens) [Search protein sequence]
QNWFPIFNPERSDKPSVPLKIPLQRNVIPSVTRVLQQTMTKQQVFLLERW
KQRMILELGEDGFKEYTSNVFLQGKRFHEALESILSPNLLKSGYIESVQH
ILKDVSGVRALESAVQHETLNYIGLLDCVAEYQGKLCVIDWKTSEKPKPF
IQSTFDNPLQVVAYMGAMNHDTNYSFQVQCGLIVVAYKDGSPAHPHFMDA
ELCSQYWTKWLLRLEEYTEKKKNQNIQKPEYSE
3D structure
PDB5zyw Structural insights into DNA degradation by human mitochondrial nuclease MGME1
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MN A D238 E344 D127 E233
BS02 MN A H180 D238 D251 W252 H78 D127 D140 W141
BS03 MN A T134 S343 T32 S232
External links
PDB RCSB:5zyw, PDBe:5zyw, PDBj:5zyw
PDBsum5zyw
PubMed30247721
UniProtQ9BQP7|MGME1_HUMAN Mitochondrial genome maintenance exonuclease 1 (Gene Name=MGME1)

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