Structure of PDB 5zyv Chain A

Receptor sequence
>5zyvA (length=197) Species: 9606 (Homo sapiens) [Search protein sequence]
VIPSVTRVLQQTMTKQQVFLLERWKQRMILELGEDGFKEYTSNVFLQGKR
FQEALESILSDENLLKSGYIESVQHILKDVSGVRALESAVQHETLNYIGL
LDCVAEYQGKLCVIDWKTSEKPKPFIQSTFDNPLQVVAYMGAMNHDTNYS
FQVQCGLIVVAYKDGSPAHPHFMDAELCSQYWTKWLLRLEEYTEKKK
3D structure
PDB5zyv Structural insights into DNA degradation by human mitochondrial nuclease MGME1
ChainA
Resolution2.72 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A S132 T134 Q138 Q145 L149 W152 V172 F173 K177 G235 K253 T254 S255 F266 Q271 Y275 S4 T6 Q10 Q17 L21 W24 V44 F45 K49 G99 K117 T118 S119 F130 Q135 Y139
BS02 CA A D238 D251 W252 D102 D115 W116
BS03 CA A D282 Y285 D146 Y149
External links
PDB RCSB:5zyv, PDBe:5zyv, PDBj:5zyv
PDBsum5zyv
PubMed30247721
UniProtQ9BQP7|MGME1_HUMAN Mitochondrial genome maintenance exonuclease 1 (Gene Name=MGME1)

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