Structure of PDB 5zyu Chain A

Receptor sequence
>5zyuA (length=223) Species: 9606 (Homo sapiens) [Search protein sequence]
NWFPIFNPERSDKVPLKIPLQRNVIPSVTRVLQQTMTKQQVFLLERWKQR
MILELGEDGFKEYTSNVFLQGKRFHEALESILSPQNLLKSGYIESVQHIL
KDVSGVRALESAVQHETLNYIGLLDCVAEYQGKLCVIDWKTSEKPKPFIQ
STFDNPLQVVAYMGAMNHDTNYSFQVQCGLIVVAYKDGSPAHPHFMDAEL
CSQYWTKWLLRLEEYTEKKKNQN
3D structure
PDB5zyu Structural insights into DNA degradation by human mitochondrial nuclease MGME1
ChainA
Resolution1.752 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A S132 T134 Q138 L149 W152 V172 F173 G176 K177 H180 G235 L236 D238 K253 T254 S255 E256 F266 Y275 S27 T29 Q33 L44 W47 V67 F68 G71 K72 H75 G122 L123 D125 K140 T141 S142 E143 F153 Y162
BS02 dna A L125 R127 R135 L20 R22 R30
External links
PDB RCSB:5zyu, PDBe:5zyu, PDBj:5zyu
PDBsum5zyu
PubMed30247721
UniProtQ9BQP7|MGME1_HUMAN Mitochondrial genome maintenance exonuclease 1 (Gene Name=MGME1)

[Back to BioLiP]