Structure of PDB 5zxm Chain A

Receptor sequence
>5zxmA (length=390) Species: 59201 (Salmonella enterica subsp. enterica) [Search protein sequence]
SYDSSSIKVLKGLDAVRKRPGMYIGDTDDGTGLHHMAFEVVDNAIDEALA
GHCKDIVVTIHADNSVSVTDDGRGIPTGIHPSEGVSAAEVIMTVLHAGGK
FDDNSYKVSGGLHGVGVSVVNALSQKLELVIQRDGKIHRQIYEHGVPQAP
LAVTGDTDKTGTMVRFWPSKSTFTNVTEFEYEILAKRLRELSFLNSGVSI
RLRDKRDGKEDHFHYEGGIKAFVEYLNKNKTPIHPNIFYFSTEKDGIGVE
VALQWNDGFQENIYCFTNNIPQRDGGTHLAGFRAAMTRTLNAYMDKEGYS
KKAKVSATGDDAREGLIAVVSVKVPDPKFSSQTKDKLVSSEVKSAVEQQM
NELLSEYLLENPSDAKIVVGKIIDAARAREAARRAREMTR
3D structure
PDB5zxm Structural insights into the transient closed conformation and pH dependent ATPase activity of S.Typhi GyraseB N- terminal domain.
ChainA
Resolution1.938 Å
3D
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Enzymatic activity
Enzyme Commision number 5.6.2.2: DNA topoisomerase (ATP-hydrolyzing).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A N46 E50 I78 I94 G101 G102 K103 Y109 G114 L115 H116 G117 G119 V120 T165 N43 E47 I75 I91 G98 G99 K100 Y106 G111 L112 H113 G114 G116 V117 T162
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
GO:0005524 ATP binding
Biological Process
GO:0006265 DNA topological change

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Molecular Function
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Biological Process
External links
PDB RCSB:5zxm, PDBe:5zxm, PDBj:5zxm
PDBsum5zxm
PubMed33548211
UniProtA0A3R0U328

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