Structure of PDB 5zxd Chain A

Receptor sequence
>5zxdA (length=464) Species: 9606 (Homo sapiens) [Search protein sequence]
NASDIKLEKFSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHI
ANRALSIPPNIDVLLCEQEVVADETPAVQAVGAAAAEAKARRILAGLGFD
PEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVIWLN
NYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMTFKKMYQ
QKQKELLKQYEKQEKKLKELKAGELLKRPKEYTVRFTFPDPPPLSPPVLG
LHGVTFGYQGQKPLFKNLDFGIDMDSRICIVGPNGVGKSTLLLLLTGKLT
PTHGEMRKNHRLKIGFFNQQYAEQLRMEETPTEYLQRGFNLPYQDARKCL
GRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNNLDIE
SIDALGEAINEYKGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFED
YKREVLEALGEVMV
3D structure
PDB5zxd Crystal Structure of ATP-Bound Human ABCF1 Demonstrates a Unique Conformation of ABC Proteins
ChainA
Resolution2.288 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ATP A H16 G41 G43 K44 T45 T46 H15 G40 G42 K43 T44 T45
BS02 ATP A Y336 N362 G363 G365 K366 S367 T368 D469 Y258 N284 G285 G287 K288 S289 T290 D391
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity

View graph for
Molecular Function
External links
PDB RCSB:5zxd, PDBe:5zxd, PDBj:5zxd
PDBsum5zxd
PubMed30017566
UniProtQ8NE71|ABCF1_HUMAN ATP-binding cassette sub-family F member 1 (Gene Name=ABCF1)

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