Structure of PDB 5zwf Chain A

Receptor sequence
>5zwfA (length=237) Species: 10116 (Rattus norvegicus) [Search protein sequence]
KLSEEQQHIIAILLDAHHKTYDPTYADFRDFRPPVRLSMLPHLADLVSYS
IQKVIGFAKMIPGFRDLTSDDQIVLLKSSAIEVIMLRSNQSFTMDDMSWD
CGSQDYKYDVTDVSKAGHTLELIEPLIKFQVGLKKLNLHEEEHVLLMAIC
IVSPDRPGVQDAKLVEAIQDRLSNTLQTYIRCRHPPPGSHQLYAKMIQKL
ADLRSLNEEHSKQYRSLSFQPENSMKLTPLVLEVFGN
3D structure
PDB5zwf Identification of the Histidine Residue in Vitamin D Receptor That Covalently Binds to Electrophilic Ligands
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I238 K242 Q255 I256 K260 P412 E416 I55 K59 Q72 I73 K77 P229 E233
BS02 9KR A Y143 S233 R270 S271 S274 W282 V296 H301 H393 Y21 S50 R87 S88 S91 W99 V113 H118 H210 PDBbind-CN: -logKd/Ki=8.74,IC50=1.8nM
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:5zwf, PDBe:5zwf, PDBj:5zwf
PDBsum5zwf
PubMed29936834
UniProtP13053|VDR_RAT Vitamin D3 receptor (Gene Name=Vdr)

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