Structure of PDB 5zwb Chain A

Receptor sequence
>5zwbA (length=271) Species: 28901 (Salmonella enterica) [Search protein sequence]
DNHRALQTDIVAVQSQVVYGSVGNSIAVPAIKAQGLRVTAVPTVLFSNTP
HYKTFYGGIIPAEWFAGYLTALNERDALRELKAITTGYMGSADQIVLLSK
WLMAIRASHPEVCILVDPVIGDTDSGMYVQAEIPQAYRTHLLPQAQGLTP
NVFELEMLSGKPCRTLEEAVAAAQSLLSDTLKWVVITSAPGESLETITVA
VVTAQVVEVFAHPRVATELKGTGDLFCAELVSGIVQGKKLTTAAKDAAQR
VLEVMTWTQQCGCDELILPPA
3D structure
PDB5zwb Structural and functional studies on Salmonella typhimurium pyridoxal kinase: the first structural evidence for the formation of Schiff base with the substrate.
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.1.35: pyridoxal kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A N164 T200 S201 I210 H225 R227 V228 T235 G236 F239 V264 M268 N151 T187 S188 I197 H212 R214 V215 T222 G223 F226 V251 M255 MOAD: Kd=0.000000064M
BS02 MG A T162 T200 T149 T187
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003824 catalytic activity
GO:0005524 ATP binding
GO:0008270 zinc ion binding
GO:0008478 pyridoxal kinase activity
GO:0008902 hydroxymethylpyrimidine kinase activity
GO:0016301 kinase activity
GO:0046872 metal ion binding
Biological Process
GO:0009443 pyridoxal 5'-phosphate salvage
GO:0016310 phosphorylation
GO:0042816 vitamin B6 metabolic process
Cellular Component
GO:0005829 cytosol

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Biological Process
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Cellular Component
External links
PDB RCSB:5zwb, PDBe:5zwb, PDBj:5zwb
PDBsum5zwb
PubMed31116912
UniProtA0A0F7J8S0

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