Structure of PDB 5zw8 Chain A

Receptor sequence
>5zw8A (length=383) Species: 104623 (Prodigiosinella confusarubida) [Search protein sequence]
MDFNLSNSQSDIYESAYRFACDVLDQDAQTRISQKILSTELWKKAAAYGF
AHGPVSHQFGGSELGALDTALMIEALGKGSRDIGLSFSLCAHLCACVIPL
YRFGSSELKDKYLESLVTGKLIAANAATEPDAGSDIYNMQATAQPCEGGY
ILNGKKIFITNAPIADVFIIYAKTNPDHGFLGVSAFLIEKGTPGLNVGEV
IPKDCLSNCPWSEIVFNDIFIPQSQRIGMEGAGGAIFHDSMIWEKGCLSA
LFVGGLARLLETTLEYAKARQQFGKAIGQFQSVSNRIIDMKLRLEQCRLM
LYRACWKHDQGQDAEADIAMSKLLISEYAVQSGLDAIQTFGGAAMDQELG
LVRHLLNMIPSRIFSGTNDIQKEIIARKLGLRG
3D structure
PDB5zw8 Crystal Structure of PigA: A Prolyl Thioester-Oxidizing Enzyme in Prodigiosin Biosynthesis.
ChainA
Resolution1.689 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) A127 T128 E244 R377
Catalytic site (residue number reindexed from 1) A127 T128 E244 R377
Enzyme Commision number 1.3.8.14: L-prolyl-[peptidyl-carrier protein] dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD A N125 A127 T128 G133 S134 F158 I159 T160 W211 I363 F364 T367 D369 N125 A127 T128 G133 S134 F158 I159 T160 W211 I363 F364 T367 D369
BS02 O4B A E40 K44 E40 K44
BS03 O4B A K275 F280 K275 F280
BS04 PRO A I136 F237 H238 G366 I136 F237 H238 G366
Gene Ontology
Molecular Function
GO:0003995 acyl-CoA dehydrogenase activity
GO:0016491 oxidoreductase activity
GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors
GO:0050660 flavin adenine dinucleotide binding
Biological Process
GO:0017000 antibiotic biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5zw8, PDBe:5zw8, PDBj:5zw8
PDBsum5zw8
PubMed30095206
UniProtQ5W271|PIGA_SERS3 L-prolyl-[peptidyl-carrier protein] dehydrogenase (Gene Name=pigA)

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