Structure of PDB 5zw4 Chain A

Receptor sequence
>5zw4A (length=216) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168) [Search protein sequence]
TDRYEQINDYIEALLKPRPDNVKRLEAYAEEHHVPIMEKAGMEVLLQILS
VKQPKKILEIGTAIGYSAIRMALELPSAEIYTIERNEKRHEEAVNNIKEF
QLDDRIHVFYGDALELADAVHVTAPYDVIFIDAAKGQYQNFFHLYEPMLS
PDGVIITDNVLFKGLVAEDYSKIEPKRRRRLVAKIDEYNHWLMNHPDYQT
AIIPVGDGLAISKKKR
3D structure
PDB5zw4 Identification of a novel tRNA wobble uridine modifying activity in the biosynthesis of 5-methoxyuridine.
ChainA
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A H34 P36 R86 R90 R178 R181 H33 P35 R85 R89 R177 R180
BS02 SAM A I37 M38 G62 A64 S68 E85 R86 R90 D113 A114 D133 A134 A135 I36 M37 G61 A63 S67 E84 R85 R89 D112 A113 D132 A133 A134
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0008168 methyltransferase activity
GO:0008171 O-methyltransferase activity
GO:0016300 tRNA (uridine) methyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0008033 tRNA processing
GO:0030488 tRNA methylation
GO:0032259 methylation

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Molecular Function
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Biological Process
External links
PDB RCSB:5zw4, PDBe:5zw4, PDBj:5zw4
PDBsum5zw4
PubMed29982645
UniProtO32036|TRMR_BACSU tRNA 5-hydroxyuridine methyltransferase (Gene Name=trmR)

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