Structure of PDB 5zty Chain A

Receptor sequence
>5ztyA (length=449) Species: 9606,10665 [Search protein sequence]
APPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKP
SYLFIGSLALADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFT
ASVGSLLLAAIDRYLCLRYPPSYKALLTRGRALVLLGIMWVLSALVSYLP
LMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQ
HVASNIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELD
KAIGRNTNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRA
ALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRAK
RVITTFRTGTWDAYARMRLDVELAKTLGLVLAVLLICWFPVLALMAHSLA
TTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSEEIRSSAHHCLAHWKK
3D structure
PDB5zty Crystal Structure of the Human Cannabinoid Receptor CB2
ChainA
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.17: lysozyme.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 9JU A F87 S90 F117 F183 W194 M265 F69 S72 F99 F165 W176 M395
Gene Ontology
Molecular Function
GO:0003796 lysozyme activity
GO:0004930 G protein-coupled receptor activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
GO:0009253 peptidoglycan catabolic process
GO:0016998 cell wall macromolecule catabolic process
GO:0031640 killing of cells of another organism
GO:0042742 defense response to bacterium
GO:0044659 viral release from host cell by cytolysis
Cellular Component
GO:0016020 membrane
GO:0030430 host cell cytoplasm

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Cellular Component
External links
PDB RCSB:5zty, PDBe:5zty, PDBj:5zty
PDBsum5zty
PubMed30639103
UniProtD9IEF7;
P34972|CNR2_HUMAN Cannabinoid receptor 2 (Gene Name=CNR2)

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