Structure of PDB 5zrk Chain A

Receptor sequence
>5zrkA (length=129) Species: 246196 (Mycolicibacterium smegmatis MC2 155) [Search protein sequence]
MTKQIVVAGALISRGTLLVAQRDRPAELAGLWELPGGKVTPGESDADALA
RELREELGVDVAVGERLGADVALNDAMTLRAYRVTLRSGSPHPHDHRALR
WVGADEIDGLAWVPADRAWVPDLVAALSG
3D structure
PDB5zrk Structural insights into the specificity and catalytic mechanism of mycobacterial nucleotide pool sanitizing enzyme MutT2.
ChainA
Resolution1.49 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.55: 8-oxo-dGTP diphosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 DCP A R22 R24 E33 K38 L73 L79 D116 R22 R24 E33 K38 L73 L79 D116
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0008413 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity
GO:0016787 hydrolase activity
GO:0035539 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity
GO:0044715 8-oxo-dGDP phosphatase activity
GO:0044716 8-oxo-GDP phosphatase activity
GO:0046872 metal ion binding
Biological Process
GO:0006260 DNA replication
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:5zrk, PDBe:5zrk, PDBj:5zrk
PDBsum5zrk
PubMed30312643
UniProtA0R2K6

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