Structure of PDB 5zr6 Chain A

Receptor sequence
>5zr6A (length=214) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
VAQDYLKVIWTAQEWSQDKVSTKMLAERIGVSASTASESIRKLAEQGLVD
HGAVTLTDSGRRAALAMVRRHRLLETFLVNELGYRWDEVHDEAEVLEHAV
SDRLMARIDAKLGFPQRDPHGDPIPGADGQVPTPPARQLWACRDGDTGTV
ARISDADPQMLRYFASIGISLDSRLRVLARREFAGMISVAIDSADGATVD
LGSPAAQAIWVVSL
3D structure
PDB5zr6 Crystal structures of manganese-dependent transcriptional repressor MntR (Rv2788) from Mycobacterium tuberculosis in apo and manganese bound forms.
ChainA
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A H86 E90 H105 D170 H71 E75 H90 D155
BS02 MN A E90 D133 H135 D137 E75 D118 H120 D122
BS03 MN A D16 E109 E112 H113 D4 E94 E97 H98
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005515 protein binding
GO:0043565 sequence-specific DNA binding
GO:0046872 metal ion binding
GO:0046914 transition metal ion binding
GO:0046983 protein dimerization activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0045892 negative regulation of DNA-templated transcription
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5zr6, PDBe:5zr6, PDBj:5zr6
PDBsum5zr6
PubMed29730293
UniProtI6Y1Q2

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