Structure of PDB 5zon Chain A

Receptor sequence
>5zonA (length=256) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
HDDLMLALALADRADELTRVRFGALDLRIDTKPDLTPVTDADRAVESDVR
QTLGRDRPGDGVLGEEFGGSTTFTGRQWIVDPIDGTKNFVRGVPVWASLI
ALLEDGVPSVGVVSAPALQRRWWAARGRGAFASVDGARPHRLSVSSVAEL
HSASLSFSSLSGWARPGLRERFIGLTDTVWRVRAYGDFLSYCLVAEGAVD
IAAEPQVSVWDLAALDIVVREAGGRLTSLDGVAGPHGGSAVATNGLLHDE
VLTRLN
3D structure
PDB5zon Identification and structural characterization of a histidinol phosphate phosphatase from Mycobacterium tuberculosis
ChainA
Resolution1.94 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.15: histidinol-phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A D44 E67 E68 D83 D42 E65 E66 D81
BS02 ZN A E67 D83 D213 E65 D81 D211
BS03 PO4 A E67 I85 D86 G87 T88 E65 I83 D84 G85 T86
Gene Ontology
Molecular Function
GO:0004401 histidinol-phosphatase activity
GO:0008934 inositol monophosphate 1-phosphatase activity
GO:0016787 hydrolase activity
GO:0016791 phosphatase activity
GO:0042578 phosphoric ester hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0000105 L-histidine biosynthetic process
GO:0010125 mycothiol biosynthetic process
Cellular Component
GO:0005829 cytosol
GO:0005886 plasma membrane

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Biological Process
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Cellular Component
External links
PDB RCSB:5zon, PDBe:5zon, PDBj:5zon
PDBsum5zon
PubMed29752410
UniProtP95189|HISN_MYCTU Histidinol-phosphatase (Gene Name=hisN)

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