Structure of PDB 5zod Chain A

Receptor sequence
>5zodA (length=260) Species: 9606 (Homo sapiens) [Search protein sequence]
GIQGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSHLMGMFYRTIRMM
ENGIKPVYVFDGKPPQNDECKHLLSLMGIPYLDAPSEAEASCAALVKAGK
VYAAATEDMDCLTFGSPVLMRHLTASEAKKLPIQEFHLSRILQELGLNQE
QFVDLCILLGSDYCESIRGIGPKRAVDLIQKHKSIEEIVRRLDPNKYPVP
ENWLHKEAHQLFLEPEVLDPESVELKWSEPNEEELIKFMCGEKQFSEERI
RSGVKRLSKS
3D structure
PDB5zod Structural basis of 5' flap recognition and protein-protein interactions of human flap endonuclease 1.
ChainA
Resolution1.9 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A E160 D179 D181 D233 E89 D108 D110 D162
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003824 catalytic activity
GO:0004518 nuclease activity
GO:0016788 hydrolase activity, acting on ester bonds

View graph for
Molecular Function
External links
PDB RCSB:5zod, PDBe:5zod, PDBj:5zod
PDBsum5zod
PubMed30295841
UniProtP39748|FEN1_HUMAN Flap endonuclease 1 (Gene Name=FEN1)

[Back to BioLiP]