Structure of PDB 5znq Chain A

Receptor sequence
>5znqA (length=183) Species: 273123 (Yersinia pseudotuberculosis IP 32953) [Search protein sequence]
ASKTAQQLKYIKDSIKTIPDYPKAGILFRDVTSLLENPKAYSASIELLSE
HYSESGVTKVVGTEARGFLFGAPVALALGVGFVPVRKPGKLPRETISESY
ELEYGTDTLEIHTDSIQPGDKVLVVDDLLATGGTIEATVKLIRRLGGEVV
HAAFIINLPELGGEARLTQQGIHCYSLVSFDGH
3D structure
PDB5znq Crystal structure of APRT from Y. pseudotuberculosis with bound adenine (P21 space group).
ChainA
Resolution1.75 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) R70 E107
Catalytic site (residue number reindexed from 1) R66 E103
Enzyme Commision number 2.4.2.7: adenine phosphoribosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADE A L31 F32 R33 L132 L162 H187 L27 F28 R29 L128 L158 H183
Gene Ontology
Molecular Function
GO:0003999 adenine phosphoribosyltransferase activity
GO:0016757 glycosyltransferase activity
Biological Process
GO:0006166 purine ribonucleoside salvage
GO:0006168 adenine salvage
GO:0009116 nucleoside metabolic process
GO:0044209 AMP salvage
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5znq, PDBe:5znq, PDBj:5znq
PDBsum5znq
PubMed
UniProtQ66DQ2|APT_YERPS Adenine phosphoribosyltransferase (Gene Name=apt)

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