Structure of PDB 5zhp Chain A

Receptor sequence
>5zhpA (length=394) Species: 10116,10665 [Search protein sequence]
TIWQVVFIAFLTGFLALVTIIGNILVIVAFKVNKQLKTVNNYFLLSLACA
DLIIGVISMNLFTTYIIMNRWALGNLACDLWLSIDYVASNARVMNLLVIS
FDRYFSITRPLTYRAKRTTKRAGVMIGLAWVISFVLWAPAILFWQYFVGK
RTVPPGECFIQFLSEPTITFGTAIAAFYMPVTIMTILYWRIYKETEKMNI
FEMLRIDEGGGSGGDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRR
AALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRA
KRVITTFRTGTWDAYLIKEKKAAQTLSAILLAFIITWTPYNIMVLVNTFC
DSCIPKTYWNLGYWLCYINSTVNPVCYALCNKTFRTTFKTLLLC
3D structure
PDB5zhp Structure-guided development of selective M3 muscarinic acetylcholine receptor antagonists
ChainA
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.17: lysozyme.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GLC A V1060 G1064 V257 G261
BS02 9EC A D147 Y148 S151 W199 T234 A235 A238 W503 Y506 N507 Y529 C532 D85 Y86 S89 W137 T172 A173 A176 W337 Y340 N341 Y363 C366
Gene Ontology
Molecular Function
GO:0003796 lysozyme activity
GO:0004930 G protein-coupled receptor activity
GO:0016907 G protein-coupled acetylcholine receptor activity
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Biological Process
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Cellular Component
External links
PDB RCSB:5zhp, PDBe:5zhp, PDBj:5zhp
PDBsum5zhp
PubMed30404914
UniProtP00720|ENLYS_BPT4 Endolysin (Gene Name=E);
P08483

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