Structure of PDB 5zfy Chain A

Receptor sequence
>5zfyA (length=123) Species: 9606 (Homo sapiens) [Search protein sequence]
RGRRRRLVWTPSQSEALRACFERNPYPGIATRERLAQAIGIPEPRVQIWF
QNERSRQLRQHRRESPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREE
LARETGLPESRIQIWFQNRRARH
3D structure
PDB5zfy Structural basis for multiple gene regulation by human DUX4.
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A R20 R21 R23 L24 W26 R62 N69 R73 R95 F118 R124 R146 R3 R4 R6 L7 W9 R45 N52 R56 R69 F92 R98 R120 PDBbind-CN: Kd=68.03nM
BS02 dna A R20 R23 Y43 R71 R79 R95 R96 R98 T99 R137 W141 N144 R148 R3 R6 Y26 R54 R62 R69 R70 R72 T73 R111 W115 N118 R122 PDBbind-CN: Kd=68.03nM
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:5zfy, PDBe:5zfy, PDBj:5zfy
PDBsum5zfy
PubMed30322619
UniProtQ9UBX2|DUX4_HUMAN Double homeobox protein 4 (Gene Name=DUX4)

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