Structure of PDB 5zdq Chain A

Receptor sequence
>5zdqA (length=264) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence]
VWGHTQLNRLSFLETVPVVPLRVSDESSEDRPTWSLPDIENVAITHKKPN
GLVDTLAYRSVRTCRWLFDTFSLYRFGSITESKVISRCLFLETVAGVPGM
VGGMLRHLSSLRYMTRDKGWINTLLVEAENERMHLMTFIELRQPGLPLRV
SIIITQAIMYLFLLVAYVISPRFVHRFVGYLEEEAVITYTGVMRAIDEGR
LRPTKNDVPEVARVYWNLSKNATFRDLINVIRADEAEHRVVNHTFADMHE
KRLQNSVNPFVVLK
3D structure
PDB5zdq Insights into the ubiquinol/dioxygen binding and proton relay pathways of the alternative oxidase.
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.-.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FE A E123 E162 H165 E266 E92 E131 H134 E235
BS02 FE A E162 E213 E266 E131 E182 E235
BS03 RNB A V92 R96 R118 L122 L212 E215 A216 T219 V61 R65 R87 L91 L181 E184 A185 T188 BindingDB: IC50=4.0nM
Gene Ontology
Molecular Function
GO:0008199 ferric iron binding
GO:0009916 alternative oxidase activity
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
Biological Process
GO:0010230 alternative respiration
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane

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Cellular Component
External links
PDB RCSB:5zdq, PDBe:5zdq, PDBj:5zdq
PDBsum5zdq
PubMed30910528
UniProtQ26710|AOX_TRYBB Alternative oxidase, mitochondrial (Gene Name=AOX)

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