Structure of PDB 5zba Chain A

Receptor sequence
>5zbaA (length=360) Species: 330879 (Aspergillus fumigatus Af293) [Search protein sequence]
DLGDSLAKVLPTGVKVTIRHISSAPSPCVALFAAPPGEEPESTFCENHFL
AVSISPNENEESEVIIFGIEVLVYGTAHLTTIFVSKADSTGYLHLLKNAP
KVSLLRLISNAFLSFLVQTHQRPGVRLMVSLFARAQNQYLFPGSIENPEK
HVLDDRGLIKWWCRVIDPILREYEPETKSSATAFLIVPGCDKFETRGFFP
ITARSDGKDRPRWLNSYPLHQLCDNPNAPPRCLVPRFPDDPKTRFLIDLD
DELPNSGHWRSVKSLAQFWEMMSFRQECSAGRLVGFLWLVINPPFFWPDT
GRGHAVLSEEDYKAAINFLIDQDFNTKHKAIASTKAWAEKVASLADQLWV
GQRVEGRNAT
3D structure
PDB5zba Multisite Substrate Recognition in Asf1-Dependent Acetylation of Histone H3 K56 by Rtt109.
ChainA
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.48: histone acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 COA A A93 D94 S95 S109 L111 R140 Q142 Y145 H157 V158 L159 L164 W167 R170 A87 D88 S89 S103 L105 R134 Q136 Y139 H151 V152 L153 L158 W161 R164
Gene Ontology
Molecular Function
GO:0004402 histone acetyltransferase activity
GO:0010484 histone H3 acetyltransferase activity
GO:0016740 transferase activity
GO:0032931 histone H3K56 acetyltransferase activity
Biological Process
GO:0006325 chromatin organization
GO:0006338 chromatin remodeling
GO:0006355 regulation of DNA-templated transcription
GO:0006974 DNA damage response
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5zba, PDBe:5zba, PDBj:5zba
PDBsum5zba
PubMed30057113
UniProtQ4WUS9

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