Structure of PDB 5z6t Chain A

Receptor sequence
>5z6tA (length=317) Species: 322104 (Scheffersomyces stipitis CBS 6054) [Search protein sequence]
PSIKLNSGYDMPAVGFGCWKVDVDTCSEQIYRAIKTGYRLFDGAEDYANE
KLVGAGVKKAIDEGIVKREDLFLTSKLWNNYHHPDNVEKALNRTLSDLQV
DYVDLFLIHFPVTFKFVPLEEKYPPGFYCGKGDNFDYEDVPILETWKALE
KLVKAGKIRSIGVSNFPGALLLDLLRGATIKPSVLQVEHHPYLQQPRLIE
FAQSRGIAVTAYSSFGPQSFVELNQGRALNTSPLFENETIKAIAAKHGKS
PAQVLLRWSSQRGIAIIPKSNTVPRLLENKDVNSFDLDEQDFADIAKLDI
NLRFNDPWDWDKIPIFV
3D structure
PDB5z6t Structural insight intoD-xylose utilization by xylose reductase from Scheffersomyces stipitis
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.307: D-xylose reductase [NAD(P)H].
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAP A G18 C19 W20 D43 Y48 H110 S165 Q187 Y213 S214 F216 Q219 S220 E223 F236 A253 I268 P269 K270 N272 R276 E279 N280 N306 G17 C18 W19 D42 Y47 H109 S164 Q186 Y212 S213 F215 Q218 S219 E222 F235 A252 I267 P268 K269 N271 R275 E278 N279 N305
Gene Ontology
Molecular Function
GO:0004032 aldose reductase (NADPH) activity
GO:0016491 oxidoreductase activity
GO:0032866 D-xylose reductase (NADPH) activity
Biological Process
GO:0042732 D-xylose metabolic process
GO:0042843 D-xylose catabolic process
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5z6t, PDBe:5z6t, PDBj:5z6t
PDBsum5z6t
PubMed30487522
UniProtP31867|XYL1_PICST NAD(P)H-dependent D-xylose reductase (Gene Name=XYL1)

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