Structure of PDB 5z6r Chain A

Receptor sequence
>5z6rA (length=273) Species: 9606 (Homo sapiens) [Search protein sequence]
NLANLIMNEIVDNGTAVKFDDIAGQDLAKQALQEIVILPSLRPELFTGLR
APARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKKLVRALFA
VARELQPSIIFIDQVDSLLCRRLKTEFLIEFDGVQSAGDDRVLVMGATNR
PQELDEAVLRRFIKRVYVSLPNEETRLLLLKNLLCKQGSPLTQKELAQLA
RMTDGYSGSDLTALAKDAALGPIRELKPEQVKNMSASEMRNIRLSDFTES
LKKIKRSVSPQTLEAYIRWNKDF
3D structure
PDB5z6r The Aaa Family Protein Spastin Severs A Microtubule
ChainA
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.6.1.1: microtubule-severing ATPase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ATP A I344 A345 G385 N386 G387 K388 T389 M390 N487 L517 G546 S547 I22 A23 G63 N64 G65 K66 T67 M68 N149 L179 G208 S209
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity

View graph for
Molecular Function
External links
PDB RCSB:5z6r, PDBe:5z6r, PDBj:5z6r
PDBsum5z6r
PubMed
UniProtQ9UBP0|SPAST_HUMAN Spastin (Gene Name=SPAST)

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