Structure of PDB 5z3i Chain A

Receptor sequence
>5z3iA (length=247) Species: 3816 (Abrus precatorius) [Search protein sequence]
RPIKFSTEGATSQSYKQFIEALRERLRGGLIHDIPVLPDPTTLQERNRYI
TVELSNSDTESIEVGIDVTNAYVVAYRAGTQSHFLRDAPSSASDYLFTGT
DQHSLPFYGTYGDLERWAHQSRQQIPLGLQALTHGISFFRSGGNDNEEKA
RTLIVIIQMVAEAARFRYISNRVRVSIQTGTAFQPDAAMISLENNWDNLS
RGVQESVQDTFPNQVTLTNIRNEPVIVDSLSHPTVAVLALMLFVCNP
3D structure
PDB5z3i Structural basis for neutralization of cytotoxic abrin by monoclonal antibody D6F10.
ChainA
Resolution1.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.2.22: rRNA N-glycosylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADE A Y74 V75 G111 Y113 I159 R167 Y72 V73 G109 Y111 I157 R165
Gene Ontology
Molecular Function
GO:0030598 rRNA N-glycosylase activity
Biological Process
GO:0017148 negative regulation of translation

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Molecular Function
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Biological Process
External links
PDB RCSB:5z3i, PDBe:5z3i, PDBj:5z3i
PDBsum5z3i
PubMed30521151
UniProtP11140|ABRA_ABRPR Abrin-a

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