Structure of PDB 5z2e Chain A

Receptor sequence
>5z2eA (length=265) Species: 1231057 (Paenisporosarcina sp. TG-14) [Search protein sequence]
MMIRVAIGGPRGKMGQEAVHTVMNNENMELVAVLDHKDIGDLLSESPNFP
ASYEVPVFLNLESLIVTIKPDVFLDLTTPHQVFEHTMLCLQNNVRPVIGT
TGFTDEQLQQCTILAEVNKLGCIVAPNFAIGAVLMMKFASLAAAYFPDVE
IIEMHHDQKLDAPSGTAYKTAQMIAEVRPSHKQGHPNEKETLEGARGASY
DGIPIHSVRLPGLIAHQQILFGGEGQLFTLRHDSYNRQSFMSGVTFSINQ
VMEIKELVYGLENIL
3D structure
PDB5z2e Crystal structure of dihydrodipicolinate reductase (PaDHDPR) from Paenisporosarcina sp. TG-14: structural basis for NADPH preference as a cofactor
ChainA
Resolution1.8 Å
3D
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Enzymatic activity
Enzyme Commision number 1.17.1.8: 4-hydroxy-tetrahydrodipicolinate reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PDC A H154 H155 K158 S163 G164 T165 H155 H156 K159 S164 G165 T166
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0008839 4-hydroxy-tetrahydrodipicolinate reductase
GO:0016491 oxidoreductase activity
GO:0016726 oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor
GO:0050661 NADP binding
GO:0051287 NAD binding
Biological Process
GO:0009085 lysine biosynthetic process
GO:0009089 lysine biosynthetic process via diaminopimelate
GO:0019877 diaminopimelate biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:5z2e, PDBe:5z2e, PDBj:5z2e
PDBsum5z2e
PubMed29786696
UniProtA0A3B6UER2

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