Structure of PDB 5z1a Chain A

Receptor sequence
>5z1aA (length=655) Species: 272559 (Bacteroides fragilis NCTC 9343) [Search protein sequence]
SLRQDILLNNNWNFRFSHQVQGDTRRVDLPHTWNAQDALAGKIDYKRGIG
NYEKALYIRPEWKGKRLFLRFDGVNSIADVFINRKHIGEHRGGYGAFIFE
ITDLVKYGEKNSVLVRANNGEQLDIMPLVGDFNFYGGIYRDVHLLITDET
CISPLDYASPGVYLVQEVVSPQEAKVCAKVNLSNRAADGTAELQVLVTDG
TKVICKESRNVSLKQGADILEQLPLLIQKPRLWNGCEDPFMYQVSISLHK
DGKQIDSVTQPLGLRYYHTDPDKGFFLNGKHLPLHGVCRHQDRAEVGNAL
RPQHHEEDVALMREMGVNAIRLAHYPQATYMYDLMDKHGIVTWAEIPFVG
PGGYADKGFVDQASFRENGKQQLIELIRQHYNHPSICFWGLFNELKEVGD
NPVEYVKELNALAKQEDPTRPTTSASNQDGNLNFITENIAWNRYDGWYGS
TPKTLATFLDRTHKKHPELRIGISEYGAGASIYHQQDSLKQPSASGWWHP
ENWQTYYHMENWKIIAERPFVWGTFVWNMFDFGAAHRTEGDRPGINDKGL
VTFDRKVRKDAFYFYKANWNKQEPMIYLAEKRCRLRYQPEQTFMAFTTAP
EAELFVNGVSCGKQKADTYSTVVWKNVKLTSGENIIRVTTPGKKPLTDEV
TVEYK
3D structure
PDB5z1a Dissection of the substrate preference and structure of gut microbial-glucuronidases identifies the major bacteria causing xenobiotic toxicity
ChainA
Resolution1.859 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.2.1.31: beta-glucuronidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SJ5 A D166 H359 E429 Y479 Y483 E510 W562 R572 N581 K583 D131 H324 E394 Y444 Y448 E475 W527 R537 N546 K548
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004565 beta-galactosidase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
Biological Process
GO:0005975 carbohydrate metabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5z1a, PDBe:5z1a, PDBj:5z1a
PDBsum5z1a
PubMed
UniProtQ5LIC7|BGLR_BACFN Beta-glucuronidase (Gene Name=lacZ_4)

[Back to BioLiP]