Structure of PDB 5yz9 Chain A

Receptor sequence
>5yz9A (length=99) Species: 9606 (Homo sapiens) [Search protein sequence]
SIVEKFRSRGRAQVQEFCDYGTKEECMKASDADRPCRKLHFRRIINKHTD
ESLGDCSFLNTCFHMDTCKYVHYEIDASMDSEAPGSKDHTPSQELALTQ
3D structure
PDB5yz9 Solution structure of the RNA recognition domain of METTL3-METTL14 N6-methyladenosine methyltransferase.
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.348: mRNA m(6)A methyltransferase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN A C276 H298 C18 H40
BS02 ZN A C314 C326 H330 C56 C68 H72
External links
PDB RCSB:5yz9, PDBe:5yz9, PDBj:5yz9
PDBsum5yz9
PubMed29542011
UniProtQ86U44|MTA70_HUMAN N6-adenosine-methyltransferase catalytic subunit (Gene Name=METTL3)

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