Structure of PDB 5yyf Chain A

Receptor sequence
>5yyfA (length=138) Species: 9606 (Homo sapiens) [Search protein sequence]
MASSCAVQVKLELGHRAQVRKKPTVEGFTHDWMVFVRGPEHSNIQHFVEK
VVFHLHESFPRPKRVCKDPPYKVEESGYAGFILPIEVYFKNKEEPRKVRF
DYDLFLHLEGHPPVNHLRCEKLTFNNPTEDFRRKLLKA
3D structure
PDB5yyf Structure-guided development of YEATS domain inhibitors by targeting pi-pi-pi stacking.
ChainA
Resolution1.903 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A H30 H56 S58 A79 G80 F81 D103 F105 L106 H107 L108 H111 H30 H56 S58 A79 G80 F81 D103 F105 L106 H107 L108 H111
BS02 peptide A R99 D101 R99 D101
BS03 FOA A F28 F59 S76 G77 Y78 F28 F59 S76 G77 Y78 PDBbind-CN: -logKd/Ki=6.48,Kd=0.33uM
Gene Ontology
Biological Process
GO:0006355 regulation of DNA-templated transcription

View graph for
Biological Process
External links
PDB RCSB:5yyf, PDBe:5yyf, PDBj:5yyf
PDBsum5yyf
PubMed30374167
UniProtP42568|AF9_HUMAN Protein AF-9 (Gene Name=MLLT3)

[Back to BioLiP]