Structure of PDB 5yy9 Chain A

Receptor sequence
>5yy9A (length=137) Species: 9606 (Homo sapiens) [Search protein sequence]
VNEYVDARDTNMGAWFEAQVVRVTRKAPSRPALEEDVIYHVKYDDYPENG
VVQMNSRDVRARARTIIKWQDLEVGQVVMLNYNPDNPKERGFWYDAEISR
KRETRTARELYANVVLGDSLNDCRIIFVDEVFKIERP
3D structure
PDB5yy9 Structure of the UHRF1 Tandem Tudor Domain Bound to a Methylated Non-histone Protein, LIG1, Reveals Rules for Binding and Regulation.
ChainA
Resolution2.653 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A D142 D145 M148 F152 E153 Y188 D190 Y191 N194 M224 R235 G236 W238 E276 F278 D6 D9 M12 F16 E17 Y43 D45 Y46 N49 M79 R90 G91 W93 E130 F132
External links
PDB RCSB:5yy9, PDBe:5yy9, PDBj:5yy9
PDBsum5yy9
PubMed30639225
UniProtQ96T88|UHRF1_HUMAN E3 ubiquitin-protein ligase UHRF1 (Gene Name=UHRF1)

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