Structure of PDB 5yy4 Chain A

Receptor sequence

>5yy4A (length=236) Species: 10090 (Mus musculus) [Search protein sequence]

EVQLQQSGAELVRPGTSVKMSCKAAGYTFTKYWIGWVKQRPGHGLEWIGD
IHPGSFYSNYNEKFKGKATLTADTSSSTAYMQLSSLTSEDSAIYYCARDY
YTNYGDWGQGTSVTVSSGGGGSDIVMTQAAPSVSVTPGESVSISCRSSKS
LLHRNGNTYLFWFLQRPGQSPQLLIYRMSNLASGVPDRFSGSGSGTAFTL
RISRVEAEDVGVYYCMQHLEYPYTFGSGTKLELKVR

3D structure

PDB

5yy4 Tyrosine Sulfation Restricts the Conformational Ensemble of a Flexible Peptide, Strengthening the Binding Affinity for an Antibody

Chain

Resolution

1.59 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	peptide	A	Y34 W35 D52 H54 S57 Y59 H171 Y177 H236 E238 Y239 Y241	Y32 W33 D50 H52 S55 Y57 H153 Y159 H218 E220 Y221 Y223
BS02	SO4	A	Y29 T30 K33 Y34	Y27 T28 K31 Y32
BS03	SO4	A	S210 R219	S192 R201

External links

PDB	RCSB:5yy4, PDBe:5yy4, PDBj:5yy4
PDBsum	5yy4
PubMed	29936828

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