Structure of PDB 5yvi Chain A

Receptor sequence
>5yviA (length=828) Species: 9606 (Homo sapiens) [Search protein sequence]
EWKPDEQGLQQILQLLKESQSPDTTIQRTVQQKLEQLNQYPDFNNYLIFV
LTKLKSEDEPTRSLSGLILKNNVKAHFQNFPNGVTDFIKSECLNNIGDSS
PLIRATVGILITTIASKGELQNWPDLLPKLCSLLDSEDYNTCEGAFGALQ
KICEDSAEILDSLDRPLNIMIPKFLQFFKHSSPKIRSHAVACVNQFIISR
TQALMLHIDSFIENLFALAGDEEPEVRKNVCRALVMLLEVRMDRLLPHMH
NIVEYMLQRTQDQDENVALEACEFWLTLAEQPICKDVLVRHLPKLIPVLV
NGMKYSDIDIILLDWNLRKCSAAALDVLANVYRDELLPHILPLLKELLFH
HEWVVKESGILVLGAIAEGCMQGMIPYLPELIPHLIQCLSDKKALVRSIT
CWTLSRYAHWVVSQPPDTYLKPLMTELLKRILDSNKRVQEAACSAFATLE
EEACTELVPYLAYILDTLVFAFSKYQHKNLLILYDAIGTLADSVGHHLNK
PEYIQMLMPPLIQKWNMLKDEDKDLFPLLECLSSVATALQSGFLPYCEPV
YQRCVNLVQKTLAQAMLNNAQPDQYEAPDKDFMIVALDLLSGLAEGLGGN
IEQLVARSNILTLMYQCMQDKMPEVRQSSFALLGDLTKACFQHVKPCIAD
FMPILGTNLNPEFISVCNNATWAIGEISIQMGIEMQPYIPMVLHQLVEII
NRPNTPKTLLENTAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNE
EKDSAFRGICTMSVNPSGVIQDFIFFCDAVASWINPKDDLRDMFCKILHG
FKNQENWRRFSDQFPLPLKERLAAFYGV
3D structure
PDB5yvi Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites.
ChainA
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Gene Ontology
Molecular Function
GO:0031267 small GTPase binding
Biological Process
GO:0006606 protein import into nucleus
GO:0006886 intracellular protein transport

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Molecular Function
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Biological Process
External links
PDB RCSB:5yvi, PDBe:5yvi, PDBj:5yvi
PDBsum5yvi
PubMed29677513
UniProtQ92973|TNPO1_HUMAN Transportin-1 (Gene Name=TNPO1)

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