Structure of PDB 5ys5 Chain A

Receptor sequence
>5ys5A (length=457) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
RPTLPIPDLLTTDARNRIQLTIGAGQSTFGGKTATTWGYNGNLLGPAVKL
QRGKAVTVDIYNQLTEETTLHWHGLEVPGEVDGGPQGIIPPGGKRSVTLN
VDQPAATCWFHPHQHGKTGRQVAMGLAGLVVIEDDEILKLMLPKQWGIDD
VPVIVQDKKFSADGQIDYQLDVMTAAVGWFGDTLLTNGAIYPQHAAPRGW
LRLRLLNGCNARSLNFATSDNRPLYVIASDGGLLPEPVKVSELPVLMGER
FEVLVEVNDNKPFDLVTLPVSQMKMAIAPFDKPHPVMRIQPIAISASGAL
PDTLSSLPALPSLEGLTVRKLQLSMDPMLDMMGMQMLMEGGKFDFHHANK
INGQAFDMNKPMFAAAKGQYERWVISGVGDMMLHPFHIHGTQFRILSENG
KPPAAHRAGWKDTVKVEGNVSEVLVKFNHDAPKEHAYMAHCHLLEHEDTG
MMLGFTV
3D structure
PDB5ys5 Crystal structures of multicopper oxidase CueO G304K mutant: structural basis of the increased laccase activity
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.16.3.4: cuproxidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CU A H443 C500 H505 H384 C441 H446
BS02 CU A H103 H141 H501 H73 H111 H442
BS03 CU A H143 H448 H499 H113 H389 H440
BS04 CU A D132 H488 D102 H429
BS05 CU A E110 H494 E80 H435
BS06 CU A H145 H406 H115 H347
Gene Ontology
Molecular Function
GO:0005507 copper ion binding
GO:0016491 oxidoreductase activity

View graph for
Molecular Function
External links
PDB RCSB:5ys5, PDBe:5ys5, PDBj:5ys5
PDBsum5ys5
PubMed30250139
UniProtP36649|CUEO_ECOLI Multicopper oxidase CueO (Gene Name=cueO)

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