Structure of PDB 5yp8 Chain A

Receptor sequence
>5yp8A (length=51) Species: 9606 (Homo sapiens) [Search protein sequence]
REEEDVICDGCNGPVVGTRYKCSVCPDYDLCSVCEGKGLHRGHTKLAFPS
P
3D structure
PDB5yp8 Insights into degradation mechanism of N-end rule substrates by p62/SQSTM1 autophagy adapter.
ChainA
Resolution1.448 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
3.6.4.10: non-chaperonin molecular chaperone ATPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C4 C7 C27 C30 C8 C11 C31 C34
BS02 ZN A C18 C21 H36 H39 C22 C25 H40 H43
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:5yp8, PDBe:5yp8, PDBj:5yp8
PDBsum5yp8
PubMed30120248
UniProtP11021|BIP_HUMAN Endoplasmic reticulum chaperone BiP (Gene Name=HSPA5);
Q13501|SQSTM_HUMAN Sequestosome-1 (Gene Name=SQSTM1)

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