Structure of PDB 5ynb Chain A

Receptor sequence
>5ynbA (length=291) Species: 1235996 (Human betacoronavirus 2c EMC/2012) [Search protein sequence]
ASADWKPGHAMPSLFKVQNVNLERCELANYKQSIPMPRGVHMNIAKYMQL
CQYLNTCTLAVPANMRVIHFGAGSDKGIAPGTSVLRQWLPTDAIIIDNDL
NEFVSDADITLFGDCVTVRVGQQVDLVISDMYDPTGSNESKALFFTYLCN
LINNNLALGGSVAIKITEHSWSVELYELMGKFAWWTVFCTNANASSSEGF
LLGINYLGTIKENIDGGAMHANYIFWRNSTPMNLSTYSLFDLSKFQLKLK
GTPVLQLKESQINELVISLLSQGKLLIRDNDTLSVSTDVLV
3D structure
PDB5ynb Structural insights into the molecular mechanism of MERS Coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex
ChainA
Resolution1.98 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.57: methyltransferase cap1.
3.4.19.12: ubiquitinyl hydrolase 1.
3.6.4.12: DNA helicase.
3.6.4.13: RNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SFG A N43 Y47 G71 G73 P80 D99 L100 D114 C115 D130 M131 Y132 N43 Y47 G71 G73 P80 D99 L100 D114 C115 D130 M131 Y132
Gene Ontology
Molecular Function
GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:5ynb, PDBe:5ynb, PDBj:5ynb
PDBsum5ynb
PubMed
UniProtK0BWD0

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