Structure of PDB 5ylc Chain A

Receptor sequence
>5ylcA (length=330) Species: 562 (Escherichia coli) [Search protein sequence]
KDTIYHAKDAVQATKPDMRKPRLVVFVVGETARADHVSFNGYERDTFPQL
AKIDGVTNFSNVTSCGTSTAYSVPCMFSYLGADEYDVDTAKYQENVLDTL
DRLGVSILWRDNNSDSKGVMDKLPKAQFADYKSATNNAICNTNPYNECRD
VGMLVGLDDFVAANNGKDMLIMLHQMGNHGPAYFKRYDEKFAKFTPVCEG
NELAKCEHQSLINAYDNALLATDDFIAQSIQWLQTHSNAYDVSMLYVSDH
GESLGENGVYLHGMPNAFAPKEQRSVPAFFWTDKQTGITPMATDTVLTHD
AITPTLLKLFDVTADKVKDRTAFIRLEHHH
3D structure
PDB5ylc Substrate analog interaction with MCR-1 offers insight into the rising threat of the plasmid-mediated transferable colistin resistance.
ChainA
Resolution1.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A E31 T70 D250 H251 E30 T69 D249 H250
Gene Ontology
Molecular Function
GO:0016772 transferase activity, transferring phosphorus-containing groups

View graph for
Molecular Function
External links
PDB RCSB:5ylc, PDBe:5ylc, PDBj:5ylc
PDBsum5ylc
PubMed29079699
UniProtA0A0R6L508|MCR1_ECOLX Probable phosphatidylethanolamine transferase Mcr-1 (Gene Name=mcr1)

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