Structure of PDB 5yki Chain A

Receptor sequence
>5ykiA (length=383) Species: 9606 (Homo sapiens) [Search protein sequence]
GRSRLLEDFRNNRYPNLQLREIAGHIMEFSQDQHGSRFIQLKLERATPAE
RQLVFNEILQAAYQLMVDVFGNYVIQKFFEFGSLEQKLALAERIRGHVLS
LALQMYGCRVIQKALEFIPSDQQNEMVRELHQHTEQLVQDQYGNYVIQHV
LEHGRPEDKSKIVAEIRGNVLVLSQHKFASNVVEKCVTHASRTERAVLID
EVCTMNDGPHSALYTMMKDQYANYVVQKMIDVAEPGQRKIVMHELHQHTE
QLVQDQYGNYVIQHVLEHGRPEDKSKIVAEIRGNVLVLSQHKFASNVVEK
CVTHASRTERAVLIDEVCTMNDGPHSALYTMMKDQYANYVVQKMIDVAEP
GQRKIVMHKIRPHIATLRKYTYGKHILAKLEKY
3D structure
PDB5yki Expanding RNA binding specificity and affinity of engineered PUF domains.
ChainA
Resolution2.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A R37 Q40 N72 Y73 R109 Q112 N144 Y145 K177 N181 E184 Y221 N223 Y224 N259 Y260 Q263 K292 N296 E299 Y336 N338 Y339 H375 R37 Q40 N72 Y73 R109 Q112 N144 Y145 K177 N181 E184 Y221 N223 Y224 N259 Y260 Q263 K292 N296 E299 Y336 N338 Y339 H375 PDBbind-CN: Kd=1.5nM
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:5yki, PDBe:5yki, PDBj:5yki
PDBsum5yki
PubMed29490074
UniProtQ14671|PUM1_HUMAN Pumilio homolog 1 (Gene Name=PUM1)

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