Structure of PDB 5yk2 Chain A

Receptor sequence
>5yk2A (length=391) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
SKDEVTAELMEKAANQLFTVLGELKGGAMKVGQALSVMEAAIPDEFGEPY
REALTKLAPPLPASKVHRVLDGQLGTKWRERFSSFNDTPVASASIGQVHK
AIWSDGREVAVKIQYPGADEALRADLKTMQRMVGVLKQLSPGADVQGVVD
ELVERTEMELDYRLEAANQRAFAKAYHDHPRFQVPHVVASAPKVVIQEWI
EGVPMAEIIRHGTTEQRDLIGTLLAELTFDAPRRLGLMHGDAHPGNFMLL
PDGRMGIIDFGAVAPMPGGFPIELGMTIRLAREKNYDLLLPTMEKAGLIQ
RGRQVSVREIDEMLRQYVEPIQVEVFHYTRKWLQKMTVSQIDRTARQMDL
PAKLAIPMRVIASVGAILCQLDAHVPIKALSEELIPGFAEP
3D structure
PDB5yk2 Discovery of the first macrolide antibiotic binding protein in Mycobacterium tuberculosis: a new antibiotic resistance drug target.
ChainA
Resolution2.807 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ERY A E196 D286 A307 A309 I407 R410 E151 D241 A262 A264 I356 R359
Gene Ontology
Cellular Component
GO:0009274 peptidoglycan-based cell wall

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Molecular Function

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Cellular Component
External links
PDB RCSB:5yk2, PDBe:5yk2, PDBj:5yk2
PDBsum5yk2
PubMed29350349
UniProtO53343

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