Structure of PDB 5yk0 Chain A

Receptor sequence
>5yk0A (length=399) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
DEVTAELMEKAANQLFTVLGELKGGAMKVGQALSVMEAAIPDEFGEPYRE
ALTKLQKDAPPLPASKVHRVLDGQLGTKWRERFSSFNDTPVASASIGQVH
KAIWSDGREVAVKIQYPGADEALRADLKTMQRMVGVLKQLSPGADVQGVV
DELVERTEMELDYRLEAANQRAFAKAYHDHPRFQVPHVVASAPKVVIQEW
IEGVPMAEIIRHGTTEQRDLIGTLLAELTFDAPRRLGLMHGDAHPGNFML
LPDGRMGIIDFGAVAPMPGGFPIELGMTIRLAREKNYDLLLPTMEKAGLI
QRGRQVSVREIDEMLRQYVEPIQVEVFHYTRKWLQKMTVSQIDRSVAQIR
TARQMDLPAKLAIPMRVIASVGAILCQLDAHVPIKALSEELIPGFAEPD
3D structure
PDB5yk0 Discovery of the first macrolide antibiotic binding protein in Mycobacterium tuberculosis: a new antibiotic resistance drug target.
ChainA
Resolution2.102 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ADP A A138 S139 A155 K157 Q242 W244 I245 A94 S95 A111 K113 Q198 W200 I201
Gene Ontology
Cellular Component
GO:0009274 peptidoglycan-based cell wall

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:5yk0, PDBe:5yk0, PDBj:5yk0
PDBsum5yk0
PubMed29350349
UniProtO53343

[Back to BioLiP]