Structure of PDB 5yjw Chain A

Receptor sequence
>5yjwA (length=454) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
SGAGPTSFKTMKVIDPSDKPNVLILGSGWGAISFLKHIDTKKYNVSIISP
RSYFLFTPLLPSAPVGTVDEKSIIEPIVNFALKKKGNVTYYEAEATSINP
DRNTVTIKSLSAAEIKYDYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSL
EIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAAGELQDYVH
QDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQSHLENTSIKVHL
RTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVITDLFK
KIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAEY
LAKNFDKMAQIPNFQKKIDLLFEENNFKPFKYNDLGALAYLGSERAIATI
RSGKRTFYTGGGLMTFYLWRILYLSMILSARSRLKVFFDWIKLAFFKRDF
FKGL
3D structure
PDB5yjw Ubiquinone binding site of yeast NADH dehydrogenase revealed by structures binding novel competitive- and mixed-type inhibitors
ChainA
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.6.5.9: NADH:ubiquinone reductase (non-electrogenic).
Interaction with ligand
Gene Ontology
Molecular Function
GO:0003954 NADH dehydrogenase activity
GO:0008137 NADH dehydrogenase (ubiquinone) activity
GO:0016491 oxidoreductase activity
GO:0042802 identical protein binding
GO:0050136 NADH:ubiquinone reductase (non-electrogenic) activity
Biological Process
GO:0006116 NADH oxidation
GO:0006120 mitochondrial electron transport, NADH to ubiquinone
GO:0043065 positive regulation of apoptotic process
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005759 mitochondrial matrix

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5yjw, PDBe:5yjw, PDBj:5yjw
PDBsum5yjw
PubMed29402945
UniProtP32340|NDI1_YEAST Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial (Gene Name=NDI1)

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