Structure of PDB 5yf4 Chain A

Receptor sequence
>5yf4A (length=129) Species: 9606 (Homo sapiens) [Search protein sequence]
GVWKYEHLRQFCLELNGLAVKLQSECHPDTCTQMTATEQWIFLCAAHKTP
KECPAIDYTRHTLDGAACLLNSAKLGSVCRRIYRIFSHAYFHHRQIFDEY
ENETFLCHRFTKFVMKYNLMSKDNLIVPI
3D structure
PDB5yf4 The MST4-MOB4 complex disrupts the MST1-MOB1 complex in the Hippo-YAP pathway and plays a pro-oncogenic role in pancreatic cancer.
ChainA
Resolution1.897 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Q105 W106 I107 F108 L109 A111 P116 E118 R161 R162 R165 Q39 W40 I41 F42 L43 A45 P50 E52 R80 R81 R84
BS02 ZN A C110 H113 C119 H127 C44 H47 C53 H61
BS03 ZN A C92 C97 H169 H174 C26 C31 H88 H93
External links
PDB RCSB:5yf4, PDBe:5yf4, PDBj:5yf4
PDBsum5yf4
PubMed30072378
UniProtQ9Y3A3|PHOCN_HUMAN MOB-like protein phocein (Gene Name=MOB4)

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