Structure of PDB 5yd2 Chain A

Receptor sequence
>5yd2A (length=349) Species: 885315 (Entamoeba histolytica HM-3:IMSS) [Search protein sequence]
IHNFGAMAKEVIEATAKAVNNFWEGLSILEISHRSKEWINVMNETKALMK
EVMDIPEGYEILFFGGGASLQFLMVAMNLLNKKACYLDTGVWASKAIKEA
ENIGEVKIIGTSKDKNYTYIPEYQIPSDYDYFHITTNNTIYGTEIRKDIE
SPIPLVADMSSDILSKPIDISKYSLIYAGAQKNCGAAGVTIVIIKKEILG
KVQRKIPIILDYQVHILNNSMYNTPPVISIFTVNQTLKYIKKIGGLKKIQ
ELNEEKARLLYAEIDRNKIFRGTVRKKDRSIMNVCFVMEEQYKQLENEFS
EYALQKGIIGIKGHRSVGGFRASIYNAVTIESVQALIKCMHDFEQLHTH
3D structure
PDB5yd2 N-terminal residues are crucial for quaternary structure and active site conformation for the phosphoserine aminotransferase from enteric human parasite E. histolytica.
ChainA
Resolution2.35 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.6.1.52: phosphoserine transaminase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PLP A G72 A73 S74 W97 T144 D163 S165 K187 G67 A68 S69 W92 T139 D158 S160 K182
BS02 PLP A N228 T229 N223 T224
Gene Ontology
Molecular Function
GO:0004648 O-phospho-L-serine:2-oxoglutarate aminotransferase activity
GO:0008483 transaminase activity
Biological Process
GO:0006563 L-serine metabolic process
GO:0006564 L-serine biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5yd2, PDBe:5yd2, PDBj:5yd2
PDBsum5yd2
PubMed30959130
UniProtM7XC02

[Back to BioLiP]