Structure of PDB 5yb8 Chain A

Receptor sequence

>5yb8A (length=549) Species: 1355242 (Pseudomonas sp. AIU 813)

KKPITIFGPDFPFAFDDWLEHPAGLGSIPAARHGEEVAIVGAGIAGLVAA
YELMKLGLKPVVYEASKMGGRLRSQAFNGTDGIIAELGGMRFPVSSTAFY
HYVDKLGLETKPFPNPLTPASRSTVIDLEGQTYYAEKAADLPALFQEVTD
AWADALESGARFGDIQQAIRDRDVPRLKELWNTLVPLWDDRTFYDFVATS
KAFAKLSFQHREVFGQVGFGTGGWDSDFPNSMLEIFRVVMTNCDDHQHLV
VGGVEQVPQGIWRHVPERCAHWPEGTSLSSLHGGAPRTGVKRIARASDGR
LAVTDNWGDCRHYAAVLTTCQSWLLTTQIDCEESLFSQKMWMALDRTRYM
QSSKTFVMVDRPFWKDKDPETGRDLMSMTLTDRLTRGTYLFDNGDDKPGV
ICLSYAWMSDALKMLPHPVEKRVQLALDALKKIYPKTDIAGHIIGDPITI
SWEADPHFLGAFKGALPGHYRYNQRMYAHFMQAQMPVEQRGIFIAGDDVS
WTPAWVEGAVQTSLNAVWGIMNHFGGKTHADNPGPGDVFDEIGQIALAD

3D structure

• PDB: 5yb8 Ligand complex structures of l-amino acid oxidase/monooxygenase from
• Chain: A
• Resolution: 2.3 Å

Enzymatic activity

• Catalytic site (original residue number in PDB): E245 K365
• Catalytic site (residue number reindexed from 1): E234 K354
• Enzyme Commision number: 1.13.12.3: tryptophan 2-monooxygenase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	ARG	A	R102 D238 Y416 W418 A515 W516	R91 D227 Y405 W407 A504 W505
BS02	ARG	A	D393 R394	D382 R383
BS03	ARG	A	E344 Q349 D356	E333 Q338 D345
BS04	FAD	A	V51 G52 G54 I55 A56 E75 A76 G81 R82 L83 G99 G100 M101 R102 F103 G300 V301 C331 L335 I340 W463 F469 A472 F473 D508 A515 W516 V517	V40 G41 G43 I44 A45 E64 A65 G70 R71 L72 G88 G89 M90 R91 F92 G289 V290 C320 L324 I329 W452 F458 A461 F462 D497 A504 W505 V506

Gene Ontology

Molecular Function

• GO:0000166 nucleotide binding
• GO:0001716 L-amino-acid oxidase activity
• GO:0004497 monooxygenase activity
• GO:0016491 oxidoreductase activity

Biological Process

• GO:0009063 amino acid catabolic process
• GO:0009851 auxin biosynthetic process

External links

• PDB: RCSB:5yb8, PDBe:5yb8, PDBj:5yb8
• PDBsum: 5yb8
• PubMed: 29511608
• UniProt: W6JQJ6